LDN-27219 PRECLINICAL RESEARCH FOR DUMMIES

EC dysfunction, characterized by blunted relaxations in response to acetylcholine and lowered NO bioavailability, was located in the aortas of male HAS-2 mice, while it had been unaltered inside the aortas of female HAS-2 mice. Superoxide levels amplified and extracellular superoxide dismutase (ecSOD) expression lowered in the aortas of male and fe